DIMACS Workshop on Data Mining Techniques in Bioinformatics October 30 - 31, 2003 DIMACS Center, CoRE Building, Rutgers University Organizers: Mona Singh, Princeton University, mona at cs.princeton.ed Mark Gerstein, Yale University, Mark.Gerstein at yale.edu Presented under the auspices of the DIMACS Special Focus on Data Analysis and Mining ********************************************************************* In recent years, high-throughput experimental methods in molecular biology have resulted in enormous amounts of data, both in terms of volume and in terms of new types of data. In addition to complete genome sequences, we have gene expression data, protein structural data, protein-protein interaction data, and protein-DNA interaction data. Data mining techniques will play a large role in analyzing and integrating these large biological datasets, as well as in discovering the biological processes underlying these data. The goal of this workshop is to bring together researchers in both data mining and bioinformatics, with the aim of exploring new techniques and insights for deciphering biological databases. Talks will be by invitation only. ***************************************************************** Workshop Program: Thursday, October 30, 2003 9:00 - 9:50 Breakfast and Registration 9:50 - 10:00 Opening Remarks Fred Roberts, Director of DIMACS 10:00 - 10:45 Computational discovery of gene modules and regulatory networks Ziv Bar-Joseph, MIT 10:45 - 11:30 Global search for genetic associations by pattern discovery: Methods and examples Andrea Califano, Columbia 11:30 - 12:15 Predicting patterns of transcriptional regulation in early fly embryos Eric Siggia, Rockefeller 12:15 - 1:45 Lunch 1:45 - 2:30 Large-scale, high-confidence predictions of bZIP protein-protein interactions Mona Singh, Princeton 2:30 - 3:15 On truth, pathways and interactions Andrey Rzhetsky, Columbia 3:15 - 3:45 Break 3:45 - 4:30 Predicting protein interactions on a genome-scale Mark Gerstein, Yale 4:30 - 5:15 Evolution of Multi-Domain Proteins Sarah Teichmann, Cambridge 5:15 Wine and Cheese Friday, October 31, 2003 9:30 - 9:50 Breakfast and Registration 9:50 - 10:00 Opening Remarks 10:00 - 10:45 Intrinsic disorder and protein function Keith Dunker, Indiana 10:45 - 11:30 Topologic organization and functional utilization of cellular networks Zoltan Oltvai, Northwestern 11:30 - 12:15 Functional profiling of cancers using gene expression data Gustavo Stolovitzky, IBM 12:15 - 1:45 Lunch 1:45 - 2:30 Integrating heterogeneous data sources for gene function prediction Olga Troyanskaya, Princeton 2:30 - 3:15 PIR Integrated bioinformatics system for functional genomics and proteomics Cathy Wu, Georgetown 3:15 - 3:45 Break 3:45 - 4:30 Integrative modeling of microarray data for mRNA expression and transcription factor occupancy Harmen Bussemaker, Columbia 4:30 - 5:15 Active reconstruction of molecular interaction networks Tommi Jaakkola, MIT ********************************************************************** Registration Fees: (Pre-registration deadline: October 23, 2003) Regular rate Preregister before deadline $120/day After preregistration deadline $140/day Reduced Rate* Preregister before deadline $60/day After preregistration deadline $70/day Postdocs Preregister before deadline $10/day After preregistration deadline $15/day DIMACS Postdocs $0 Non-Local Graduate & Undergraduate students Preregister before deadline $5/day After preregistration deadline $10/day Local Graduate & Undergraduate students $0 (Rutgers & Princeton) DIMACS partner institution employees** $0 DIMACS long-term visitors*** $0 Registration fee to be collected on site, cash, check, VISA/Mastercard accepted. Our funding agencies require that we charge a registration fee for the workshop. Registration fees cover participation in the workshop, all workshop materials, breakfast, lunch, breaks, and any scheduled social events (if applicable). * College/University faculty and employees of non-profit organizations will automatically receive the reduced rate. Other participants may apply for a reduction of fees. They should email their request for the reduced fee to the Workshop Coordinator at workshop at dimacs.rutgers.edu. Include your name, the Institution you work for, your job title and a brief explanation of your situation. All requests for reduced rates must be received before the preregistration deadline. You will promptly be notified as to the decision about it. ** Fees for employees of DIMACS partner institutions are waived. DIMACS partner institutions are: Rutgers University, Princeton University, AT&T Labs - Research, Bell Labs, NEC Laboratories America and Telcordia Technologies. Fees for employees of DIMACS affiliate members Avaya Labs, IBM Research and Microsoft Research are also waived. ***DIMACS long-term visitors who are in residence at DIMACS for two or more weeks inclusive of dates of workshop. ********************************************************* Information on participation, registration, accommodations, and travel can be found at: http://dimacs.rutgers.edu/Workshops/Techniques/ **PLEASE BE SURE TO PRE-REGISTER EARLY** *********************************************************